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Rising Kratom Use Fuels Opioid-Like Risks With 7-OH

New research warns of addictive potential in concentrated kratom metabolite 7-OH, often sold as a “legal” opioid alternative.

Naveen Sankar S's avatar
Naveen Sankar S
Jul 26, 2025
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Recent findings highlight growing concerns over kratom and its potent metabolite 7-hydroxymitragynine (7-OH), which may trigger opioid-like addiction, withdrawal, and toxicity. While kratom is often used as a self-treatment for opioid withdrawal, emerging evidence suggests it can lead to its own form of substance use disorder, especially when 7-OH is pr…

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