Raising Potassium Lowers Arrhythmia Risk in ICD Patients

A large randomized trial shows that boosting potassium levels in patients with implantable cardioverter-defibrillators reduces arrhythmia events and ICD shocks.

The POTCAST trial, presented at ESC 2025 found that actively increasing plasma potassium levels in high-risk patients with cardiovascular disease and ICDs reduced arrhythmia-related events by 24%.

Study Details

The trial included 1,200 patients with cardiovascular disease and an implantable cardioverter-defibrillator (ICD). All participants had baseline p…