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Psilocybin for Smoking Cessation Shows Early Promise

A pilot randomized clinical trial suggests psilocybin with cognitive behavioral therapy may help more smokers quit than nicotine patch with the same counseling support.

Naveen Sankar S's avatar
Naveen Sankar S
Mar 22, 2026
∙ Paid

In a small but important randomized clinical trial, smokers who received a single dose of psilocybin plus cognitive behavioral therapy were significantly more likely to remain abstinent at 6 months than those treated with nicotine patch plus the same therapy. The results suggest psilocybin may become a new option worth studying further for tobacco use d…

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