Optic Nerve Stroke Risk Higher With Semaglutide in Type 2 Diabetes

New veteran study suggests relative higher risk of optic nerve injury with semaglutide compared with SGLT2 inhibitors, while absolute risk remains low

In a large Veterans Health Administration study, semaglutide use in type 2 diabetes was associated with a higher relative risk of nonarteritic anterior ischemic optic neuropathy, but the absolute risk over follow-up was under 0.3%, underscoring the need for balanced risk discussions.

Study Details

A new observational study published in JAMA Ophthalmology …