Just Healthcare

Just Healthcare

Share this post

Just Healthcare
Just Healthcare
New Understanding of Colorectal Cancer Progression
Copy link
Facebook
Email
Notes
More

New Understanding of Colorectal Cancer Progression

Exploring How Ancient Viral Elements Drive Tumor Growth Through Oncogenic Signaling

Naveen Sankar S's avatar
Naveen Sankar S
Aug 01, 2024
∙ Paid

Share this post

Just Healthcare
Just Healthcare
New Understanding of Colorectal Cancer Progression
Copy link
Facebook
Email
Notes
More
1
Share
A detailed and scientific illustration of a colorectal cancer cell showing the role of endogenous retroviruses (ERVs) as enhancers in the gene regulatory network. The image should highlight the MAPK/AP1 signaling pathway activating the ERVs, which in turn regulate tumor-specific genes like ATG12 and XRCC4. The cancer cell should have a vibrant, complex interior with visible ERV elements activating gene expression. Include molecular and cellular elements to emphasize the scientific focus.

Topline:

Endogenous retroviruses (ERVs), remnants of ancient viral infections in our genome, have been found to play a critical role in the development and progression of colorectal cancer by acting as enhancers in cancer-specific regulatory networks, driven by oncogenic signaling pathways.

Study Details:

Recent research has revealed that ERVs, particularl…

Keep reading with a 7-day free trial

Subscribe to Just Healthcare to keep reading this post and get 7 days of free access to the full post archives.

Already a paid subscriber? Sign in
© 2025 Just Healthcare
Privacy ∙ Terms ∙ Collection notice
Start writingGet the app
Substack is the home for great culture

Share

Copy link
Facebook
Email
Notes
More