Most Kids With Severe Childhood Arthritis Improve With Biologic Drugs

Data from the FROST study highlight long-term benefits of IL-1 and IL-6 inhibitors, and reveal early clues about nonresponse

Topline:

The FROST study found that most children with newly diagnosed systemic juvenile idiopathic arthritis (sJIA) experienced clinically inactive disease by 3 years with IL-1 or IL-6 inhibitors—often without long-term glucocorticoids. New biomarker research may soon help predict who won’t respond to IL-1 inhibitors.

Study Details

Systemic juvenile idiop…