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Hormone Therapy Enhances Tirzepatide Weight Loss

Concurrent menopausal hormone therapy increases tirzepatide efficacy in postmenopausal women

Naveen Sankar S's avatar
Naveen Sankar S
Jul 16, 2025
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In a retrospective cohort of 400 postmenopausal women on tirzepatide, those receiving menopausal hormone therapy achieved 35 % greater total body weight loss and were 2.5 times more likely to hit ≥ 20 % weight reduction compared with women on tirzepatide alone.

Study Details


Postmenopausal status is associated with reduced response to GLP-1 and dual GIP/G…

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