Gastric Bypass, Drugs, or Diet: What Works Best for Long-Term Obesity Treatment

Long-term study data reshapes how we weigh the benefits and risks of bariatric surgery, anti-obesity medications, and plant-based lifestyle approaches

Topline

Over 10 years of follow-up in a major bariatric trial shows that Roux-en-Y gastric bypass (RYGB) results in more durable weight loss than sleeve gastrectomy. However, combining surgery with anti-obesity medications and sustained lifestyle changes may offer the best chance of lasting results.

The Challenge of Sustained Weight Loss

With over 100 mill…