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Gabapentin After Brain Injury May Reduce Long Term Cognitive Risk

A large retrospective study suggests same-day gabapentin use after traumatic brain injury was linked to lower cognitive impairment risk in mild TBI and lower mortality risk in severe TBI.

Naveen Sankar S's avatar
Naveen Sankar S
Apr 29, 2026
∙ Paid

A multinational health-record study of nearly 50,000 adults with traumatic brain injury found that people who received gabapentin on the same day as their injury had better long-term outcomes in some groups.

Same-day gabapentin was associated with a 22% lower adjusted risk of durable cognitive impairment after mild TBI and a 46% lower adjusted risk of d…

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