Forget the Tremor: Vague Symptoms Often Mark Parkinson’s Onset

Emerging evidence reveals that nonmotor signs like sleep issues, constipation, and smell loss may precede classic Parkinson’s symptoms by over a decade.

Topline

Early indicators such as REM sleep behavior disorder, constipation, and loss of smell may appear years before the classic motor symptoms of Parkinson’s disease, highlighting a critical opportunity for earlier diagnosis and intervention.

Study Details

Although Parkinson’s disease has long been identified by its motor symptoms tremor, rigidity, akine…