Early Biomarkers in Psychosis Depression May Guide Earlier Care

A large European study suggests blood inflammation markers and brain gray matter patterns may help distinguish early depression from early psychosis before illness becomes more severe.

In a multicenter JAMA Psychiatry study, researchers found that recent-onset depression and recent-onset psychosis showed different combinations of inflammatory blood markers and gray matter changes on MRI, suggesting these disorders may follow distinct biological pathways from the earliest stages.

Summary

Psychiatric diagnosis is still based mostly on sym…