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Common Painkiller Linked to Heart Failure Risk in Older Adults

New study finds pregabalin use may increase risk of heart failure in seniors with chronic pain, especially those with cardiovascular disease.

Naveen Sankar S's avatar
Naveen Sankar S
Aug 18, 2025
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A large Medicare study found that older adults prescribed pregabalin for chronic pain had a 48% higher risk of developing heart failure compared to those prescribed gabapentin, with risk rising to 85% in patients with existing cardiovascular disease.

Study Details

Chronic pain affects nearly one in three adults over 65, and non-opioid medications like pre…

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