Bedtime Dosing of Blood Pressure Medications Shows Measurable Benefits

New trial suggests evening administration of olmesartan-amlodipine may improve nocturnal blood pressure control without added risks

A multicenter randomized trial in China found that taking olmesartan-amlodipine at bedtime reduced nighttime systolic blood pressure by an additional 3 mm Hg compared with morning dosing, with improved circadian rhythm and no increase in nocturnal hypotension.

Study Details

Researchers from Sichuan University examined whether the timing of antihypertensiv…